Santiago has a lot of shopping centers or "Malls", as known by the locals. The main ones are:
- Mall Plaza Vespucio
- Mall Plaza Oeste
- Mall Portal La Dehesa
- Mall Parque Arauco
- Mall Alto Las Condes
- Mall Florida Center
- Mall Plaza Norte
- Costanera Centre
- Persa Bio-Bio
In the malls, you can find a variety of retail stores and Falabella, París and Ripley, the most famous department stores in Chile. The biggest ones are Parque Arauco and Alto Las Condes, they both have good restaurants and the former has a good agenda of free music and shows. You can get to the former from Escuela Militar metro station and to the latter from Los Domínicos; ask locals for directions if you're unsure of how to take buses.
Alonso de Córdova Street and Nueva Costanera Avenue are very exclusive areas where you can find high fashion and luxury stores like Louis Vuitton, Hermés or local designers. In this area, you find great restaurants and art galleries.
If you prefer buying handcrafts, the ones in the Centro Artesanal Santa Lucia are good and relatively cheap compared with other handcrafts stores. Other handcrafts centers are in Bellavista (though a bit more expensive).
Close to Los Domínicos metro station is Pueblito Los Domínicos steps from Los Domínicos metro station; it is more expensive but has a wide variety of local handcrafts and antiques, as well as a small exhibition room and a bonsai exhibition behind it. It is very pretty with an artificial stream in a colonial-looking atmosphere. Half of the people there are usually tourists during the summer, so you won't be alone!
Plaza Nuñoa has some small shops in the plaza where you can buy books from Latin America (Neruda, Allende, Cortazar) and also handicrafts.
If you're already kinda familiar with Santiago, you can also go to Patronato which is located near to the downtown area and it's easy to reach by metro (Patronato metro Station). There you'll find cheap clothes, food, and products of all kinds, as well as some foreign stores (mainly Chinese, Koreans, Peruvians and from the Middle East), thus allowing you to save quite a bit of money. It would be better to go alongside a local, though, since it's easy to get lost due to the very short and slim streets and the very high quotient of visitors. Beware of pickpocketers.
Similarly, those who want more surprises and know the basics about Santiago can go to the famous Persa Bio-Bio (Bio-Bio Persian market), located in the Franklin area, also not too far from downtown and near to the metro (Franklin station). It can be described as a giant flea market that opens every weekend business hours. It offers antiques, tools, handmade furniture, craftsmanship, Cheap Chinese stuff, many food stores, etc. Again, it's not a place for novices: a local's presence would be desired, as it may get difficult to find someone English-spoken in the market. You will find most of antiquities and very cool rare stuff in Persa Victor Manuel between Victor Manuel and San Isidro. A place very skipped by tourists but a visit is extremely advised. Persa Bio-Bio may take you 4-6 hrs to discover, but it also offers very nice and cheap international food courts.